KNOW THE FIGHT AGREEMENT - IS THE ROLE OF JELIT FOR THE ORGANISM
In order to understand the problem of food allergy, first you need to learn about the importance of healthy intestines, especially their mucosa, in digesting and absorption of nutrients.
The small intestine is lined with mucosal membrane (hereinafter referred to as the small intestine mucosa), which consists of several cell types. Some of them within the so-called crypts secrete intestinal juice, and the second - called intestinal villi - are adapted to digest certain foods; these are highly specialized cells. In the intestinal villi, there are also systems transporting nutrients. Thanks to the presence of villi, the surface of absorption of nutrients is 60 times larger than the surface of our skin and reaches 200 square meters !! (which equals the area of the sports court to play the hand whine). The height of the intestinal villi is 1 mm; unfortunately, they are easily damaged.
JELITA CIENKI'S LITHUANIA
In the mucosa of the small intestine there are also: cells secreting regulatory factors (eg gastrin, secretin) and cells of the immune system that bind antigens. It is also worth knowing that the tissues of human intestines contain as much as 70-80% of lymphoid tissue cells that produce immune antibodies that fight against germs and parasites. Therefore, the intestinal mucosa is so highly sensitive to allergens.
What is the degenerative "flattening" of the small intestinal mucosa, and thus the allergy of the body?
First, there is the phenomenon of food intolerance. For example, in infants under the influence of protein particles of casein contained in cow's milk in the intestine, inflammation which destroys the intestinal villi is often produced. The symptom of this is the so-called intestinal colic. A small child begins to suffer from an intestinal colic shortly after the nursing mother consumes milk, cottage cheese for breakfast.
(The colic is usually for breastfed babies, and if the child is tested for milk allergy at the moment, the results would probably be negative, but if the mother continues to consume dairy products despite the milk intolerance of the child, the allergen will for cow's milk proteins, the symptoms may be the same, with the difference that the antibodies to the cow's milk appear in the blood. As you can see, it is only at this stage that there is the possibility of laboratory allergy detection.
Allergies are often accompanied by "flattening" of the small intestinal mucosa.
This is what scientists call the phenomenon of intestinal villi destruction. First, the brush border (top of the ear) is destroyed.
A healthy strand
Brush border – this is the most important part of the intestinal villi, because here enzymes are digested and actively digested, including sugar (saccharase); enzymes digesting milk sugar - lactose (lactase) and enzymes digesting vegetable protein - gluten - abundantly present in everyday cereal foods (especially in high gluten wheat - raw material for pasta and noodles and most bread). In addition, many other digestive enzymes. So, in the mouth you digest some carbohydrates (if you have a habit of biting and chewing). You digest the majority of protein in your stomach. In contrast, fats, sugars and some proteins (eg gluten) digest in the intestines. No brush border leads to the so-called secondary deficiency of digestive enzymes, such as, for example, lactase. The task of lactase is the digestion of energy-rich milk sugar - lactose, which is abundant in food milk.
Unfortunately, children may experience so-called primary and secondary deficiency of this enzyme.The primary deficiency of digestive enzymes occurs in some infants who are born with inherited inability to produce the lactase enzyme. This causes the babies to progressively damage the intestinal villi. Secondary deficiency of digestive enzymes is conditioned not only by the primary cause, but also by others. It leads to deeper digestive problems, but worst of all, it can damage the next intestinal villi. In this sequence of events, one pathology can trigger the next. For example, the deficiency of the enzyme digesting milk may lead to a deficiency of enzymes that digest gluten or sugar. Undigested foods pass through the small intestine mucus and are treated by the immune system as an intruder-aggressor, i.e. a virus, bacterium or parasite. At this point, a defensive phagocytic process appears. It consists in the fact that immune cells (very large phat cells) absorb large organic particles of milk protein.
Then, inside them, the intruder is destroyed by specific cellular digestion. If this process is inefficient, the body has additional war tactics in reserve. Specialist soldiers of the resistance system are beginning to produce, whose erroneous task is the destruction of milk proteins wrongly suspected of the role of a pathogen. These are special antibodies that are called IgE. Of course, they can not cope with a child's daily soup on cow's milk. In the next sequence of mistakes, next IgG and IgM antibodies appear - also directed against the cow's milk protein. In total, after some time it may lead to the creation of so-called immune complexes and serious diseases due to autoimmunity. The intestines in which the allergic process described above rolls over time seem like a sieve through which the undigested food particles and the true environmental allergens enter the tissues and blood.
What disorders occur with damaged small intestine mucosa?
• protein absorption disorders • fat absorption disorders; the essential unsaturated fatty acids and others should be picked up by the portal vein to the liver and further processed for the body's needs; leaky small intestinal mucosa causes useless excretion of fats with faeces.
