Prevention and treatment of baldness. Used in male pattern baldness in men and women.
Composition:
1 ml of the preparation contains 20 mg of minoxidil for topical use.
Action:
The preparation uses the local action of minoxidil. It stimulates hair growth in male pattern baldness in men and women. In androgenetic alopecia, it positively affects the hair follicles, causing them to grow as a result of stimulating DNA synthesis. Hair improvement can also be associated with increased blood flow through the skin. The beginning of hair loss suppression is observed after about 2 months, the growth appears after 4 months, and the maximum effect - after about 12 months of systematic use of the preparation. After discontinuing treatment, after a few months it is possible to return to the initial state. Minoxidil is a pyrimidine derivative. When used systemically, it significantly reduces blood pressure through direct influence on smooth muscle of the arteriole and a significant decrease in peripheral resistance. It causes secondary stimulation of the sympathetic system, acceleration of heart rate, increase of cardiac output and cardiac output, reduction of vascular wall sensitivity to catecholamines. It does not reduce renal flow. It is characterized by a high affinity to the walls of blood vessels. Metabolized in 90% in the liver to glucuronins excreted by the kidneys.
Contraindications:
Hypersensitivity to minoxidil or other ingredients of the preparation. Do not use during pregnancy and breast-feeding, as well as in people under 18 years of age and over 65 years of age. Do not use the product on other areas of the skin, in the case of seborrheic dermatitis, psoriasis. Caution in people with coronary heart disease or hypoxia of the myocardium.
Precautions:
Pregnancy and lactation:
Side effects:
Local skin reactions may occur: redness, flaking. There were no systemic signs of using minoxidil on the skin, however, it is advisable to check the patient's condition for theoretically possible side effects: severity of coronary symptoms, tachycardia, hematocrit and hemoglobin lowering, increased urea and creatinine in the blood, ECG changes (flattening or reversal of the T-wave, changes in the ST segment), appearance of pericardial fluid, retention of sodium and body water, edema, gastrointestinal disorders, breast engorgement.
Dosage:
Apply 1 ml of the solution twice a day to the scalp at the baldness site (or in a place at risk of hair loss). Spread the preparation with your fingers over the scalp. Apply on dry skin.
(C)
