the product in the database has an inactive status
indications:
As a painkiller and anti-inflammatory in rheumatoid diseases, osteoarthritis, root pain, inflammation of the nerves and neuralgia, post-traumatic states (inflammation, edema after swellings, overloads, contusions). Is used in the treatment of localized rheumatic changes (bursitis, painful shoulder syndrome, tenosynovitis, periarticular inflammation). It can be used in combination with general treatment with diclofenac.
Composition:
1 g of gel contains 10 mg of diclofenac.
Action:
A non-steroidal anti-inflammatory drug (aminophenylacetic acid derivative) with anti-inflammatory, analgesic and antipyretic effects. The mechanism of action is the inhibition of prostaglandin cyclooxygenase (inhibition of eicosanoid synthesis, reduction of arachidonic acid in granulocytes). It has antiplatelet action on platelets. Used externally (on the skin) - relieves pain, reduces swelling, reduces inflammation. The gel form of the drug facilitates absorption, with intensive use or abuse, the overall effect of the drug should be taken into account. After being absorbed in 99%, it binds to plasma proteins. It is metabolised in the liver up to 4 metabolites, of which 4'-hydroxy derivatives have high anti-inflammatory and analgesic activity. Metabolites in the form of glucuronides and sulphates are excreted in the urine (approximately 65%) and bile (approximately 35%). T0,5 is about 1-2 hours.
Contraindications:
Hypersensitivity to Diclofenac or other components of the preparation (especially to propylene glycol). Do not use on damaged skin or wounds. Due to the difficult to control amount of systemic absorbed Diclofenac, caution should be exercised in patients with active gastric and / or duodenal ulcer disease, severe liver or kidney impairment, electrolyte disturbances, edema, cardiac insufficiency, asthma, hypersensitivity: to Acetylsalicylic acid, aminofenazone, phenylbutazone. Do not use during pregnancy and breast-feeding. Do not use in children under 6 years of age.
Precautions:
Pregnancy and lactation:
Side effects:
Local reactions may occur: redness of the skin, burning sensation, pruritus, skin rash. In the case of long-term use on large surfaces or open wounds, symptoms may occur as with the systemic use of diclofenac.
Dosage:
Adults: cover the skin with a thin layer of gel over the aching area and rub it gently; depending on the extent to which the gel is used, a single use of 2-4 g of gel is recommended; repeat the procedure 3-4 times a day. Avoid contact of the gel with eyes and mucous membranes. For external use.
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