Treatment of symptoms of venous and lymphatic circulation disorders, especially in the lower limbs with signs of heaviness and pain in the legs, nocturnal spasms, varicose veins.
Composition:
One capsule contains 200 mg of O-β-hydroxyethylrutoside. The preparation contains lactose.
Action:
The preparation has a protective effect on blood and lymph vessels. O-β-hydroxyethylrututide stabilizes vascular endothelial cells and prevents them from peeling, inhibits aggregation and increases the plasticity of red blood cells, improving their tension and elasticity. It reduces the permeability of capillaries. It improves the flow of blood and lymph. It improves the saturation of venous blood with oxygen, has a beneficial effect on gas exchange and access of nutritional products, as well as on metabolism at the cellular level. There is also a reduction in infiltration of fibrinogen through the vascular wall. In addition, it has a protective effect on liver cells. Less than 10% of the administered drug is adsorbed. The maximum concentration in the blood is reached after 1-6 h. T0,5 is 10-25 h. It is excreted in the bile.
Contraindications:
Hypersensitivity to the components of the preparation. And trimester of pregnancy.
Precautions:
Due to the lactose content, the preparation should not be used in patients with galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.
Pregnancy and lactation:
The preparation is contraindicated in the first trimester of pregnancy. The medicine must not be used in the second and third trimester of pregnancy. Due to the lack of data, the drug should not be used in breast-feeding women.
Side effects:
Uncommon: pruritus, rash, transient nausea and gastrointestinal disorders, headaches, sleep disorders. In addition, allergic reactions may occur.
Dosage:
Orally. 2 capsules 2-3 times a day for 2-4 weeks. Then you can continue the existing dosage or use 2 capsules twice a day for several weeks.
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