The drug is intended for use during surgical and post-operative procedures to: counteract pupil constriction, as well as as an anti-inflammatory after cataract surgery and after surgery on the anterior segment of the eye and in the treatment of pain after photorefractive keratectomy in the first days after surgery.
Composition:
1 ml eye drops contain 1 mg indomethacin.
Action:
A non-steroidal anti-inflammatory drug from the indole derivative group for topical use. Indomethacin is a prostaglandin synthetase inhibitor.
Contraindications:
Hypersensitivity to NSAIDs. A history of asthma associated with Acetylsalicylic acid or other NSAIDs. Active peptic ulcer of the stomach or duodenum. Severe hepatic and renal failure. Do not use from the 6th month of pregnancy. Do not use together with oral anticoagulants, other NSAIDs (including salicylates at a dose greater than 3 g per day), diflunisal, Heparin, lithium, Methotrexate in high doses, ticlopidine.
Precautions:
There are no studies on the safety of children. In the case of hypersensitivity to the drug, indomethacin treatment should be discontinued. If there is a risk of bacterial infection, appropriate antibacterial treatment should be used. NSAIDs may delay corneal healing and increase the risk of bleeding from ocular tissues during surgery in patients particularly predisposed or treated with anticoagulants. The use of contact lenses during treatment with the preparation is not recommended.
Pregnancy and lactation:
Use from the sixth month of pregnancy is contraindicated. During the first 5 months of pregnancy, use only when it is necessary. Avoid use during breastfeeding.
Side effects:
Rare: transient burning, stinging, visual disturbances after administration, hypersensitivity reactions (pruritus, redness), photosensitivity, epithelial damage to the cornea (eg corneal abrasion, punctate keratitis), increased intraocular pressure, discomfort in the eye, swollen eyelids, edema the cornea. In rare cases, NSAIDs may induce changes in the cornea, such as keratitis, a corneal ulcer that can lead to corneal perforation, particularly in patients with damaged cornea.
Dosage:
Prevention of pupil constriction during surgery: 4 drops on the day before the procedure and 4 drops during 3 hours before the procedure. Prevention of inflammation caused by cataract surgery and surgical procedures on the anterior segment of the eye: 1 drop 4-6 times a day, starting 24 hours before the procedure (the preparation is used until the symptoms of inflammation are completely resolved). Treatment of eye pain after photorefractive keratectomy: 1 drop 4 times a day in the first days after surgery. If you use more than one eye medicine, each of these medicines should be given at least 15 minutes apart.
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