Anti-acne treatment for topical use. Benzoyl peroxide has a keratolytic, oxidizing and bacterial actionPropionibacterium acnes. In addition, it stabilizes the amount of secreted fat, counteracts excessive keratosis of the epidermis and excessive sebum secretion accompanying acne. It is absorbed through the skin into the body in variable amounts and only after conversion to benzoic acid. Benzoic acid after absorption into the body goes mainly into hypuric acid, which is excreted by the kidneys.
Contraindications:
Hypersensitivity to the components of the preparation.
Precautions:
The safety and efficacy of using the drug in children have not been determined, because common acne is rare in this age group. Avoid contact with the eyes, mouth, mucous membranes and damaged skin. Carefully apply to the neck and other sensitive areas. Benzoyl peroxide can increase sensitivity to solar radiation. While using the product, do not use quartz lamps, avoid or limit long-term exposure to solar radiation. If it is not possible to avoid strong sunlight, patients should be advised to use preparations with sunscreen and wearing clothing that protects against solar radiation. The simultaneous use of other keratolytic agents, such as salicylates or sulfur compounds, may lead to increased skin irritation. In most patients, during the first few weeks of treatment, sudden exacerbation of the symptoms of exfoliation and redness of the skin may occur. It usually does not cause skin damage and these symptoms disappear within 1-2 days after the treatment is temporarily stopped. Patients should be informed that excessive use of the drug does not improve the effectiveness and may increase the risk of skin irritation. Due to the content of cetyl alcohol and stearyl alcohol, the drug may cause local skin reactions (eg contact dermatitis). Due to the content of propylene glycol alginate, the drug may cause skin irritation. With the simultaneous topical use of other anti-acne agents, care should be taken due to the possibility of an irritating effect. This can be difficult, especially when using exfoliating or abrasive remedies. If local irritation occurs (eg severe erythema, severe dryness and itching, strong burning sensation and / or smoking), discontinue use.
Pregnancy and lactation:
The drug can be used topically during pregnancy and breastfeeding only if the expected benefits of treatment for the mother outweigh the potential risks to the fetus and the child. In the last month of pregnancy, the preparation should not be used. If the medicine is used during breastfeeding, it should not be applied to the breast and breast area to prevent accidental adoption by the infant.
Side effects:
Very common: skin exfoliation, erythema at the place of use. Common: dryness, pruritus and local skin irritation. Rarely: burning sensation, skin discoloration, skin reactions at the injection site, such as irritation or pain, allergic reactions, including hypersensitivity to the site of administration and anaphylaxis, rash at the injection site. Some patients may also occasionally experience: facial edema, inflammation, allergic contact dermatitis.
Dosage:
Outwardly. Adults and adolescents. Wash the affected area of the skin with a cream 1-2 times a day. The improvement usually occurs after 4-6 weeks of treatment, however, it may be necessary to use the medicine for a longer time.
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