1 g of gel contains 10 mg of Clindamycin in the form of phosphate. The preparation contains propylene glycol and methyl parahydroxybenzoate.
Action:
Lineosamide antibiotic in the form of a topical formulation. Works, among others for bacteriaPropionibacterium acnesthat belong to the etiological factors of acne vulgaris. Clearing of skin lesions is observed within 6 weeks (long-term use of clindamycin on the skin may lead to bacterial resistance). The allantoin contained in the gel relieves irritation.
Contraindications:
Hypersensitivity to the active substance or to any of the excipients. Hypersensitivity to lincosamide antibiotics ( Clindamycin, lincomycin). Children under 12 years.
Precautions:
Avoid contact of the gel with eyes, mucous membranes and damaged skin. Oral and parenteral intake of clindamycin is associated with the risk of developing severe pseudomembranous enteritis. The likelihood of such side effects when using clindamycin on the skin is low. The patient should be advised that if diarrhea occurs during treatment, the use of the preparation should be stopped immediately and a doctor should be consulted to determine the cause and appropriate treatment. Special care should be taken in patients with enterocolitis, Crohn's disease, ulcerative colitis, antibiotic-associated colitis, and myasthenia gravis. The safety and efficacy of the medicine in children below 12 years have not been established. The preparation contains propylene glycol, which may cause skin irritation. The risk of skin irritation increases when the gel is under the closed dressing. The preparation contains methyl parahydroxybenzoate, which may cause allergic reactions (possible late-type reactions).
Pregnancy and lactation:
There are no data on the safety of topical application of clindamycin during pregnancy. The preparation can be used during pregnancy only if clearly necessary. You should not breast-feed during treatment.
Side effects:
The following may occur: excessive skin dryness, burning, itching, erythema, contact dermatitis, greasy skin, folliculitis, allergic reactions (possible late-type reactions), skin irritation, irritation of the skin around the eyes, gastro-intestinal disorders (eg loose stools) , abdominal pain, bloating, dyspepsia). After the application of clindamycin as a gel to the skin, very rare general side effects such as diarrhea, including severe diarrhea (with an admixture of blood, mucus), and colitis were very rare. The use of oral or parenteral clindamycin may be associated with the risk of severe pseudomembranous enteritis.
Dosage:
Externally, on the skin. Adults and children over 12 years: apply the gel spot or thin, or spray on the affected skin twice daily (do not rub in). Wash your hands thoroughly after using the preparation. The optimal treatment result occurs after 8-12 weeks of use.