1 tabl contains 0.58 mg of dihydroergocristine mesylate, 1.5 mg of esculin and 30 mg of rutin. The product contains lactose and sucrose.
Action:
A preparation that increases venous tone and reduces the permeability of capillaries. Dihydroergocristin - a derivative of ergot alkaloids with non-selective α-blocking activity. It expands the arteries and increases the tension of the smooth muscles of the vein walls. Esculin and rutin reduce capillary permeability.
Contraindications:
Hypersensitivity to the components of the preparation. Severe hepatic and / or renal failure. Myocardial disease, severe hypotension, cardiac insufficiency. Peptic ulcer of the stomach and duodenum. acute or chronic psychoses, states of depression. Pregnancy and breastfeeding.
Precautions:
Use with caution in patients with atrio-ventricular arrhythmias, hepatic and / or renal dysfunction. Due to lactose and sucrose content, the preparation should not be used in patients with galactose intolerance, fructose intolerance, Lapp lactase deficiency, sucrase-isomaltase deficiency or malabsorption of glucose-galactose.
Pregnancy and lactation:
Use during pregnancy and breastfeeding is contraindicated. Dihydroergocristine crosses the placenta and is excreted in breast milk.
Side effects:
The following may occur: headache and dizziness, sinus bradycardia with significant cardiac deceleration of up to 40 bpm, weakness, apathy, hypotension, nausea, reduced appetite, vomiting, diarrhea, edema and increased nasal and pharyngeal secretion, occasionally - reactions hypersensitivity and redness of the skin. Prolonged use may cause damage to the liver and kidneys.
Dosage:
Orally. Adults and children over 12 years: initially 2 tabl. 3 times a day for 1 week, then 1 tablet. 3 times a day for 2-3 months. Take tablets during a meal.