Chronic constipation. acute hepatic failure with pre-coma and coma. Chronic hepatic failure with increased ammonia in the blood.
Composition:
15 ml of syrup contains 7.5 g of lactulose.
Action:
Lactulose - a synthetic disaccharide - in the colon is a source of energy for saccharolytic bacteria that inhibit the development of proteolytic flora. By inhibiting the decomposition process, it reduces the production of ammonia, and by lowering the pH of the colonic environment, it reduces the absorption of ammonium salts that are excreted in the faeces. It stimulates intestinal peristalsis and has an osmotic laxative effect. Lactulose is not digestible and is not absorbed from the digestive tract. Unchanged, it gets into the large intestine.
Contraindications:
Hypersensitivity to the components of the preparation. Bowel obstruction. Galactosemia.
Precautions:
In the case of long-term use, it is recommended, especially in elderly patients, to periodically check the concentration of electrolytes in the blood.
Pregnancy and lactation:
Use only in case of extreme necessity.
Side effects:
In the initial period of use, abdominal pain may occur. Sometimes nausea, diarrhea, bloating was observed after high doses.
Dosage:
Orally. Adults: laxative - usually 30-45 ml (2-3 tablespoons) before breakfast or 15 ml (1 tablespoon) 3 times daily before meals, after achieving the effect of using 15 ml of fasting syrup; in liver failure - 100-180 ml per day in 4-6 doses. Children: laxative, initially: infants - 2.5 ml, children up to 3 years - 5 ml, over 3 years - 15 ml per day; then the dose can be gradually increased every 3 days until normal bowel movements are achieved. If abdominal distension occurs, the dose should be reduced to that tolerated by the child. It is recommended to administer the syrup after dilution with water or fruit juice.