the product in the database has an inactive status
indications:
Symptoms of the lower urinary tract associated with benign prostatic hyperplasia.
Composition:
One extended-release capsule contains 0.4 mg Tamsulosin hydrochloride.
Action:
Selective and competitive antagonist of α-type adrenergic α-adrenergic receptors1. Tamsulosin relaxes the smooth muscles of the prostate and urethra. Increases the maximum urinary flow rate. The reduction in symptoms from bladder filling and emptying persists during long-term treatment. Bioavailability is almost 100%, the food prolongs the absorption of the drug. After taking a single dose, the maximum plasma concentration occurs after about 6 hours. Steady state is obtained on the fifth day of taking the drug. Tamsulosin is approximately 99% bound to plasma proteins. It is metabolized in the liver and excreted mainly in the urine. T0,5 after a single intake of the preparation after a meal it is about 10 h, at steady state, about 13 hours.
Contraindications:
Hypersensitivity to the components of the preparation. Angioneurotic edema related to previous tamsulosin use. Orthostatic hypotension. Severe hepatic failure.
Precautions:
Due to the lack of clinical trials, caution should be used in patients with severe renal impairment (creatinine clearance <10 ml / min). It is not recommended to start treatment with tamsulosin in patients who are scheduled to undergo cataract surgery (risk of intraoperative flaccid iris syndrome - IFIS during cataract surgery).
Pregnancy and lactation:
Not applicable - preparation intended for use in men.
Oral: 1 capsule once a day, take after breakfast or after the first meal. The capsules should be swallowed whole with a glass of water, sitting or standing. The capsules should not be chewed or chewed. If you have difficulty swallowing, you can open the capsule and swallow its contents without chewing.
(C)
