Weakness of memory and mental ability related to age. Helpful in cerebral circulation disorders (with symptoms of dizziness, tinnitus). In addition, Bilobil and Bilobil Forte: helpful in limb blood disorders (with symptoms of cold in the extremities, pain during walking); Bilobil Intense: helpful in patients performing the recommended exercise program in the treatment of non-specific peripheral arteritis with symptoms of intermittent claudication.
Composition:
Bilobil. 1 capsule contains 40 mg of dry extract from Ginkgo Biloba leaves (35-67: 1), standardized for flavonoid glycosides (24-29%), lactone terpenes (6-9%) and bilobalide; capsules contain lactose.Bilobil Forte. 1 capsule contains 80 mg of dry extract from ginkgo leaves, corresponding to: 17.6-21.6 mg of flavonoids in the form of flavonoid glycosides; 2.24-2.72 mg of ginkgolides A, B and C; 2.08-2.56 mg of bilobalide; kaps. Forte contain lactose and glucose.Bilobil Intense. 1 capsule contains 120 mg of dry extract from ginkgo leaves (35-67: 1), which corresponds to: 26.4-32.4 mg of flavonoids in the form of flavonoid glycosides; 3.36 to 4.08 mg (6%) - 7.2 mg of ginkgolides A, B, C; 3.12-3.84 mg of bilobalide; Intense capsules contain lactose and glucose.
Action:
Extract from ginkgo biloba improves blood circulation and supplying the brain with oxygen and glucose. The flavonoid glycosides and terpene lactones (ginkgolid and bilobalide) are considered to be components with known therapeutic activity of the extract, which improve cerebral flow and prevent platelet aggregation. Improved brain flow protects cells and tissues from damage caused by oxygen deficiency and prevents the impairment of mental function related to age. The improvement of peripheral circulation counteracts the symptoms associated with the weakening of the blood supply to the limbs. After oral administration of ginkgo extract, 60% of the dose is absorbed, the maximum concentration in blood is reached for the first time after 1.5 hours, while the second peak occurs after 12 hours (which indicates the participation of hepatic and intestinal circulation in this process). Within 72 h, 38% of the taken dose of the extract is excreted through the lungs, 22% in the urine and 29% in the faeces. Ginkgo flavone glycosides are absorbed in the small intestine; the maximum concentration in blood is reached after 2 hours, the biological half-life is 2-4 hours, the whole dose is excreted within 24 hours.
Contraindications:
Hypersensitivity to any of the ingredients.
Precautions:
Use in children is not recommended. Because the extract of ginkgo prolongs the bleeding time, special care should be taken in people prone to bleeding (eg with blood coagulation disorders, haemophilia). It is recommended to stop the treatment 36 hours before the planned surgery or dental surgery. If hypersensitivity reactions occur, the drug should be discontinued. Bilobil, Bilobil Forte, Bilobil Intense contain lactose and should not be used in patients with hereditary galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. In addition, Bilobil Forte, Bilobil Intense contain glucose.
Pregnancy and lactation:
Due to the lack of clinical trials, use during pregnancy and breast-feeding is not recommended.
Side effects:
Very rare: gastrointestinal disturbances (nausea, constipation, diarrhea), headache, skin hypersensitivity reactions (pruritus, erythema, rash, edema), bleeding (especially when used concomitantly with antiplatelet or anticoagulant drugs).
Dosage:
Orally. Adults.Bilobil1 capsule 3 times a day. The improvement usually takes place after a month of treatment. In order to achieve more lasting effects, especially in the elderly, it is recommended to use the drug for about 3 months.Bilobil Forte: in patients with memory and mental impairment related to age - 1 capsule 2-3 times a day; in dizziness, tinnitus, hearing loss and in patients with symptoms of blood supply to the limbs - 1 capsule 2 times a day (morning and evening). The improvement usually takes place after 3 weeks of taking the drug. You can extend the treatment up to 3 months.Bilobil Intense: 1 capsule 2 times a day (morning and evening). The improvement usually takes place after 3 weeks of taking the drug. The treatment can be extended up to 3 months. In the case of patients performing the recommended exercise program with non-specific peripheral vascular disease with symptoms of intermittent claudication, the drug appears only after many weeks of treatment (in clinical trials observed after 10-12 weeks). Kaps. you should drink with water.
(C)
