1 tabl powl. contains 60 mg of dry St. John's wort, corresponding to 0.05-0.25 mg of total hypericin. One capsule contains 425 mg of St. John's wort extract, equivalent to 0.75-1.3 mg of total hypericin.
Action:
The active substances contained in the St. John's wort reduce the severity of mild depressive symptoms (depressed mood, lack of motivation to act) and accompanying symptoms (drowsiness, impaired concentration). The mechanism of action probably consists of on the inhibition of neurotransmitter reuptake at o.u.n. The effect occurs after 10-14 days.
Contraindications:
Hypersensitivity to the components of the preparation, episodes of major depression with suicidal thoughts, age under 6 years (Deprim) or under 12 years (Deprim forte).
Precautions:
Intense UV exposure should be avoided when using the product. Due to the lactose content, patients with rare hereditary galactose intolerance, Lapp lactase deficiency or malabsorption of glucose-galactose should not use the preparation.
Pregnancy and lactation:
Due to the lack of data on safety, it is not recommended to use the product during pregnancy and breastfeeding.
Side effects:
Rarely may occur headaches and dizziness, gastrointestinal disturbances, dry mouth mucous membranes, tiredness, allergic reactions of the skin (redness, burning of the skin), anxiety, confusion, and very rare reactions similar to sunburn after sun exposure, in patients with bipolar disorder there is a risk of having a manic episode.
Dosage:
Orally. Deprim: adults - 2 tabl. 3-4 times a day; youth over 12 years - 2 tabl. Three times a day; children from 6 to 12 years - 3-4 tabl. daily, morning or noon. The preparation should be taken with meals. Deprim forte: adults and adolescents over 12 years - 1 capsule once a day (at a fixed time), if necessary up to 2 capsules a day, morning and evening. Deprim and Deprim forte should be used for 4-6 weeks.