Symptomatic treatment of pathological impairment of cognitive functions and chronic weakening of neurosensory functions in elderly patients (with the exception of Alzheimer's disease and other severe dementia). Treatment of central symptoms resulting from cerebral circulatory disorders such as reduced visual acuity, visual field disorders, decreased hearing acuity, some vertigo and / or tinnitus syndromes. As an aid to the treatment of symptoms of peripheral circulatory disorders: intermittent claudication in chronic obliterative arteritis of the lower limbs (stage 2). As an aid to the symptoms of Raynaud's syndrome.
Composition:
1 tabl or 1 ml of liquid contains dry gingko extract (DER 35-67: 1) with a content of 21.6-26,4% of flavonoid glycosides, 2.8-3.4% of ginkgolides A, B and C, and 2.6- 3.2% bilobalide. The liquid contains 51-61% ethanol (v / v).
Action:
The preparation improves arterial, venous and capillary blood circulation, improving blood circulation o.u.n. It improves blood flow in vessels by reducing the aggregation of platelets and red blood cells. The oral bioavailability of ginkgolides A and B and bilobalide is 80-90%. The maximum concentration in the blood is reached after 1-2 h after administration. T0,5 in the elimination phase, from approx. 4 h for bilobalid and ginkgolid A up to 10 h for ginkgolid B. These substances are not metabolized and are mainly excreted in the urine and in a small amount in the faeces.
Contraindications:
Hypersensitivity to the components of the preparation.
Precautions:
The liquid contains 51-61% (v / v) alcohol, i.e. 0.45 g alcohol per dose. Due to the risk of prolonged bleeding time, the liquid should be used with caution in patients prone to bleeding. Due to the lactose content, tablets should not be used in patients with congenital galactosemia, malabsorption of Glucose or galactose or with lactase deficiency.
Pregnancy and lactation:
The product is not recommended during pregnancy and breast-feeding.
Side effects:
Gastrointestinal disorders, headaches and skin reactions may occur.
Dosage:
Oral: 3 tablets or 3 doses of fluid (1 dose = 1 ml) per day in divided doses, with a meal. The tablets should be washed with 1/2 glass of water, the liquid should be diluted in 1/2 glass of water and taken.
(C)
