Delivery of calories as part of a total or partial parenteral nutrition, hypoglycaemia.
Composition:
1000 ml of solution contains 440 g of Glucose monohydrate for injection (= 400 g of anhydrous glucose in water for injection).
Action:
Glucose is the main substrate for energy transformation in the body, it is essential for the proper functioning of all tissues of the body, especially those that are dependent on its direct metabolism, such as nervous tissue. Participating in gluconeogenesis requires adequate insulin supply, which in some disease states limits its use. In solutions above 15% it needs to be administered to large vessels, because in high concentrations it has an irritating effect on peripheral veins caused by high hyperosmosmicity of the solution. It can also increase diuresis by osmotic effects if the supply exceeds the glucose utilization rate (max. 0.75 g / kg / h). At the sudden discontinuation of the hypertonic infusion, glucose may close to secondary hypoglycaemia. The daily demand for carbohydrates is 1.5-3.0 g / kg m.c. and it depends on the energy needs of the organism and other components of the diet. 1000 ml of the product provides 1600 kcal, the osmolarity is 2220 mosmol / l.
Contraindications:
Diabetes, impaired glucose metabolism, excessive hydration of the body, hypotonic dehydration of the body, where there are no missing electrolytes, potassium deficiency in the blood, hyperosmolar coma, acidosis.
Precautions:
Pregnancy and lactation:
Side effects:
If hyperglycemia is reduced, hyperglycaemia may occur as well as renal losses, and bilirubin and lactate may increase if the recommended dosage is not adhered to.
Dosage:
As a component of parenteral nutrition according to caloric demand. In hypoglycaemia at an appropriate dilution.