Index of drugs

Prevention and treatment of potassium deficiency. Potassium deficiencies in the body are most often caused by: administration of diuretics, glucocorticoids, chronic diarrhea, persistent vomiting, and the course of some kidney diseases. Potassium deficiency is also accompanied by diseases such as secondary hyperaldosteronism, diabetes.

1 two-chamber sachet (5 g of granules) contains 782 mg of potassium ions (20 mmol) in the form of potassium chloride and potassium bicarbonate. The product contains sucrose and quinoline yellow.

Potassium is an intracellular cation that participates in many physiological processes. It is the main determinant of the intra-cellular space. The ratio of potassium concentrations in the extracellular and intracellular fluids influences the degree of polarization of the cell membrane, which in turn plays a role in important cellular processes such as nerve impulse conduction and muscle cell contraction (including in the myocardium) and transmembrane active transport of a number of substances from involving the ATP-azy Na ion pump⁺/ K⁺ subsidiary. Maintaining normal calamus contributes to maintaining normal blood pressure and prevents hypertension and cardiovascular diseases (including atherosclerotic lesions or the risk of stroke). The amount of potassium excreted in the urine is regulated by the kidneys so as to balance its supply, which ensures an even balance of potassium. After a single administration or ingestion of more potassium, only 50% of the dose is excreted in the urine within a few hours. Despite this, only a small increase in calamus is found in the blood serum, because most of the administered potassium ion travels to the cells. In the case of repeated supply of a large amount of potassium, its excretion in the urine increases, most likely due to the process of secretion of aldosterone, stimulated by potassium. In addition, the absorption of potassium from the intestinal content into the blood is likely to some extent also regulated and with repeated excessive supply may be reduced by 50%. If the amount of potassium consumed with food decreases, the potassium contained in the cells serves as a buffer against significant fluctuations in serum potassium. Deficiency or reduced aldosterone secretion is the cause of impaired excretion of potassium and its retention by the kidneys. acute acidosis impairs, while chronic acidosis or acute alkalosis potentiate the excretion of potassium in the urine. Increased sodium intake or during treatment with loop diuretics is accompanied by increased urinary excretion of potassium.

Hypersensitivity to any of the ingredients. Hyperkalemia. Severe renal failure with proteinuria and oliguria. Inflammatory lesions and ulceration of the gastric and / or duodenal mucosa.

In the event of black stools, fusowatychuous vomiting or severe abdominal pain, discontinue use. Special care should be taken when concomitant use of potassium-sparing diuretics (eg spironolactone, amiloride, triamteren), ACE inhibitors (eg Enalapril, captopril) and cardiac glycosides and NSAIDs is necessary. In patients with impaired renal function, lower doses of potassium should be considered. The product contains sucrose - should not be used by patients with rare hereditary disorders associated with fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency. Due to the content of quinoline yellow, the preparation may cause allergic reactions.

The medicine can be used during pregnancy only in cases where, in the doctor's opinion, the benefit for the mother outweighs the potential risk to the fetus. Because it has not been studied whether the drug is excreted in human milk, it should be carefully considered during breast-feeding.

The following may occur: symptoms of irritation of the gastrointestinal mucosa (burning sensation in the stomach and esophagus, nausea, abdominal pain, diarrhea, dyspeptic disorders), hyperkalemia. At the proposed dosage and method of administration, damage to the gastrointestinal mucosa leading to bleeding is unlikely.

Orally. Hypokalemia of slight degree: 1 two-chamber pouch of granules per day. Hypokalemia of a significant degree (depending on the degree of potassium deficiency): 1-3 two-chamber sachets of granules per day.
Pour the granules from the two chambers of the sachet into 0.5 cups of boiled warm water and mix. Drink a sparkling liquid. In order to reduce the irritating effect on the mucous membrane of the gastrointestinal tract, the preparation should be taken slowly, with small portions during the meal or immediately after its consumption and washed down with a large amount of water or fruit juice.