Every healthy organism infects itself with the infection of common cold viruses. It is possible thanks to the immune system - a personal doctor. When the HIV virus (human immunodeficiency virus) gets inside the body is different. This virus in the first place overpowers our personal doctor - the immune system, also called immunological!
9. POKONAÆ BARIER ? RESISTANCE OF HIV VIRUS
Warning! Viruses retain acquired drug resistance
It turns out that HIV viruses, like bacteria, permanently retain acquired drug resistance. They are immune to their destructive chemical enzymes. Therefore, it is more and more common for a patient to be infected for the first time with HIV viruses "immunized" with one or more drugs that can be used.
Suspicion of being infected with a drug-resistant virus
The use of multi-drug (combination) treatment without the expected effects in the reduction of viral load may suggest resistance of the virus to 1 or more drugs. This suspicion should be discussed with your doctor. Ignoring this fact and accepting the specifics for which the virus is "immunized" - it is not just throwing money "into the mud", but most importantly waste of time to save life - or a drastic reduction of the chance to heal.
HIV susceptibility test for drugs
On the question - how to avoid the barrier of resistance - medicine offers precise diagnostic tests - the so-called HIV virus sensitivity to drugs. These tests allow to determine whether the virus detected in a patient is resistant to a given drug, or vice versa - the drug inhibits its development. Thanks to this, you can choose effective drugs and treatment results in a decreasing amount of HIV in the blood and healing the patient.
Rising HIV resistance along with treatment
Despite the high sensitivity to the tested drugs at the beginning of treatment - the enzymes of the virus may soon be mutated and immunized. The general rule is to carry out the first virus resistance check for the drugs used after 3-4 weeks, the next after 16 weeks and subsequent, every 3 months. Only such constant supervision allows you to assess whether the drug combination, and therefore the entire treatment, is effective.
The test of the number of HIV viruses in the blood
The basic to assess the effectiveness of therapy is a constant control of the number of viruses in the blood (ie the so-called level of viral load). If the number of viruses in the blood drops below 50 copies of virus in 1 ml of blood, and CD4 T cells are within the optimal range of 350-500 in 1 ml of blood, then success can be said. The reverse situation - an increase in the number of viruses indicates the emergence of their resistance to one or more drugs and the need to replace it with another one, effective.
The patient helps himself
The most important task of the patient is possible early detection of the virus. When we detect a disease too late - even the best therapy can be ineffective. After exceeding 100,000 copies of HIV in 1 ml of blood and no CD4 T-cells mentioned above, the chances of maintaining health become slim. Conversely, the earlier we detect a disease and start treating it with a low level of virility - the greater the chances of being cured.
When are they threatening side effects and complications of AIDS?
The side effects of the drug are due to poor viraemia control. After exceeding the contractual health limit in viral load (a significant overflow of 50 copies of virus in 1 ml of blood, and CD4 T-lymphocytes below 350-500 in 1 ml of blood), the patient attacks infections resulting from the disappearance of immunity to bacteria and viruses so far harmless.
TABLE OF CONTENTS OF THE ENTIRE DEVELOPMENT:
Only strict compliance with the rules of treatment gives a chance for health
No less important is the careful adherence to the doctor's instructions.It is not easy, because the therapy schedule is similar to the timetable of a train on a fairly long and complicated route. However, the fulfillment of almost all recommendations in 90-95% - gives as much as 80% decrease in the number of HIV retroviruses and an increase in the number of lymphocytes by 60% !. Meeting requirements in 70% or slightly below, causes a health risk of lymphocyte depletion and persistence of viremia at the current, unsatisfactory level.
HIV cooperation with a doctor
It is also important mutual understanding and good contact between the doctor and the patient. It has been proven, for example, that patients in many cases are able to set themselves much higher requirements for treatment than it seems possible for doctors. This is important because their implementation also reduces some of the severe side effects of the treatment. Even more important is the knowledge of the disease and its conditions, because it facilitates contact with the doctor and makes the recommendations of the patient more aware.
MEMBERS:
In a few or a dozen years, the HIV virus can completely destroy the immune system.
Untreated infection with HIV virus results in the destruction of the immune system after many years. The body becomes defenseless against microbes that do not cause any disease symptoms under normal conditions. We then have an acquired immunodeficiency syndrome, ie AIDS (acquired immune deficiency syndrome). From that moment, recurrent fungal, viral, bacterial, protozoan and uncontrolled tumor growth, also caused by the immune system impairment - cause progressive wasting of the body, which leads to death of the patient.
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TABLE OF CONTENTS OF THE ENTIRE DEVELOPMENT:
1. HOW DO YOU SI�?? Infection?
2. FROM HIV TO AIDS - DAMAGE RESISTANT
3. DEVELOPMENT OF HIV INFECTION
4. ADVANCED INFECTION WITH HIV VIRUS - SYMPTOMS OF AIDS
5. TREATMENT OF HIV INFECTION - ATTACK TO LOWER VIRUS POINTS
6. BRAKES HIV VIRUS ONLY A COMPLEX OF DRUGS
7. TREATMENT OF HIV INFECTION IN CHILDREN
8. THE RULE OF THE TREATMENT OF TREATMENT
9. POKONAÆ BARIER ? RESISTANCE OF HIV VIRUS
10. IMMUNOTHERAPY AND VACCINES
